Epac Polyclonal Antibody

RAPGEF3 (Rap Guanine Nucleotide Exchange Factor 3) is a Protein Coding gene. Among its related pathways are Platelet activation, signaling and aggregation and Signaling by GPCR. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and cAMP-dependent protein kinase regulator activity. An important paralog of this gene is RASGEF1A. uanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. TPases are a group of enzymes that catalyze hydrolysis of the gamma phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP). Mg2+ ions are essential for catalytic activity. GTPases, often coupled to G proteins, are essential in signal transduction.

The Epac Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of Epac protein in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The Epac Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other proteins to ensure its specificity for Epac. This antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior performance characteristics, the Epac Polyclonal Antibody offers researchers a valuable tool for studying the role of Epac in various cellular processes. Its high affinity and selectivity make it an ideal choice for investigating Epac signaling pathways and exploring its involvement in disease mechanisms.

The Epac Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution, and is stable for long-term storage at -20°C. Each vial contains a sufficient amount of antibody for multiple experiments, ensuring cost-effectiveness and minimizing wastage.

In summary, the Epac Polyclonal Antibody is a reliable and specific reagent that enables accurate detection and quantification of Epac protein. Its exceptional performance characteristics, versatility, and user-friendly format make it an indispensable tool for researchers in the field of cellular signaling and disease biology.