Eotaxin Polyclonal Antibody

CCL11 is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

The Eotaxin Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Eotaxin protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Eotaxin, also known as CCL11, is a chemokine that plays a crucial role in the recruitment and activation of eosinophils, a type of white blood cell involved in allergic responses and inflammation. Dysregulation of Eotaxin has been implicated in various diseases, including asthma, allergic rhinitis, and eosinophilic esophagitis.

The Eotaxin Polyclonal Antibody exhibits exceptional specificity, binding only to the Eotaxin protein and not cross-reacting with other chemokines or related molecules. This specificity is crucial for accurate and reliable detection of Eotaxin in complex biological samples.

This antibody is validated for various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). It has been extensively tested and proven to provide robust and reproducible results across a wide range of sample types, including cell lysates, tissue homogenates, and serum.

The Eotaxin Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is stable and can be stored at -20°C, allowing for long-term storage without compromising its performance.

In summary, the Eotaxin Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of Eotaxin protein. Its high specificity, sensitivity, and validated performance make it an essential component for researchers and clinicians studying the role of Eotaxin in various diseases and biological processes.