ELOVL5 Polyclonal Antibody

ELOVL5 (ELOVL fatty acid elongase 5) belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in ELOVL5 have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for ELOVL5.

The ELOVL5 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ELOVL5 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ELOVL5 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The ELOVL5 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 35 kDa in Western blot analysis of human, mouse, and rat tissues. In addition, it shows strong staining of ELOVL5 protein in formalin-fixed, paraffin-embedded human tissues by immunohistochemistry.

This antibody is an essential tool for researchers studying the function and regulation of ELOVL5 protein in various biological processes, including lipid metabolism, skin barrier function, and brain development. Its high specificity and sensitivity make it an ideal choice for detecting ELOVL5 protein in complex biological samples.