eIF5 Polyclonal Antibody

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al. 1996 [PubMed 8663286]).

The eIF5 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of eIF5 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human eIF5 protein. The eIF5 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays.

The eIF5 protein is a key regulator of protein synthesis initiation and plays a critical role in the translation of mRNA into protein. Dysregulation of eIF5 expression has been implicated in various diseases, including cancer, neurodegenerative disorders, and viral infections. Therefore, the eIF5 Polyclonal Antibody is an essential tool for researchers studying the role of eIF5 in these diseases and for the development of novel therapeutic strategies.

The eIF5 Polyclonal Antibody is supplied as a purified IgG fraction in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. The antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence assays. The eIF5 Polyclonal Antibody is available in different sizes to meet the needs of different research projects.

In summary, the eIF5 Polyclonal Antibody is a highly specific and sensitive antibody that is essential for the detection of eIF5 protein in various biological samples. This antibody is an essential tool for researchers studying the role of eIF5 in various diseases and for the development of novel therapeutic strategies.