eIF4E Polyclonal Antibody

Eukaryotic translation initiation factor 4E encoded by EIF4E is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. EIF4E acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of EIF4E are found on other chromosomes. Alternative splicing results in multiple transcript variants.

The eIF4E Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of eIF4E protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability.

eIF4E, also known as eukaryotic translation initiation factor 4E, plays a crucial role in the initiation of protein synthesis. It binds to the mRNA cap structure and facilitates the recruitment of other translation initiation factors, ultimately leading to the initiation of translation. Dysregulation of eIF4E has been implicated in various diseases, including cancer, making it an important target for research and therapeutic development.

The eIF4E Polyclonal Antibody exhibits high affinity and specificity towards eIF4E, enabling accurate and precise detection of this protein in complex biological samples. It has been extensively validated in various experimental conditions, ensuring consistent and reproducible results.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is compatible with multiple species, including human, mouse, and rat, making it versatile for use in different research settings.

The eIF4E Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

In summary, the eIF4E Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of eIF4E protein. Its exceptional performance, versatility, and ease of use make it an invaluable asset for researchers and scientists working in the field of protein synthesis and related areas.