Dynactin 2 Polyclonal Antibody

DCTN2 encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DCTN2.

The Dynactin 2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Dynactin 2 protein in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Dynactin 2 Polyclonal Antibody exhibits a high affinity and specificity towards Dynactin 2, a crucial component of the dynactin complex involved in intracellular transport and organization of the microtubule cytoskeleton. By targeting Dynactin 2, this antibody enables researchers to investigate its role in various cellular processes, such as vesicle trafficking, mitosis, and cell migration.

This antibody has been produced using state-of-the-art techniques, ensuring a high level of purity and consistency. It has been rigorously tested to guarantee minimal cross-reactivity with other proteins, ensuring accurate and reliable results. Additionally, the antibody has been validated for use in multiple species, including human, mouse, and rat, making it a versatile tool for a wide range of research applications.

The Dynactin 2 Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is also available in various sizes to accommodate different experimental needs.

In summary, the Dynactin 2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Dynactin 2 protein. With its exceptional performance, versatility, and ease of use, this antibody is an invaluable asset for researchers studying the intricate mechanisms of intracellular transport and microtubule organization.