Dsg2 Polyclonal Antibody

DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

The Dsg2 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of Desmoglein 2 (Dsg2) protein expression. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Dsg2 is a transmembrane glycoprotein that plays a crucial role in maintaining the integrity and stability of desmosomes, which are cell-cell adhesion structures found in various tissues, including the skin and heart. Dysregulation of Dsg2 expression has been implicated in several pathological conditions, such as autoimmune diseases and cancer.

The Dsg2 Polyclonal Antibody exhibits exceptional affinity and specificity towards Dsg2, enabling accurate and reliable detection of this protein in various sample types, including cell lysates, tissue homogenates, and biological fluids. It is suitable for use in various immunological techniques, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing wastage. The Dsg2 Polyclonal Antibody is rigorously tested for quality and performance, guaranteeing consistent and reproducible results.

In summary, the Dsg2 Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in studying the role of Dsg2 in various physiological and pathological processes. Its high specificity, sensitivity, and reliability make it an ideal choice for accurate detection and analysis of Dsg2 protein expression.