DR3 Polyclonal Antibody

Tumor necrosis factor receptor superfamily member 25 encoded by TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.

The DR3 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of DR3 protein expression. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and consistency in every batch. With its exceptional affinity and selectivity, the DR3 Polyclonal Antibody offers researchers a reliable and accurate means to investigate the role of DR3 in various biological processes.

The DR3 Polyclonal Antibody exhibits excellent performance in a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry. Its robust and reproducible results make it an ideal choice for both qualitative and quantitative analysis of DR3 protein expression in various sample types, such as cell lysates, tissue sections, and whole blood.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone reconstitution steps. The DR3 Polyclonal Antibody is also compatible with a variety of commonly used detection systems, enabling seamless integration into existing experimental protocols.

Furthermore, the DR3 Polyclonal Antibody has been rigorously validated to ensure its superior performance and reliability. It has been extensively tested for specificity, sensitivity, and cross-reactivity to ensure accurate and precise results. Each batch is accompanied by a detailed Certificate of Analysis, providing comprehensive information on quality control parameters, including lot-specific data.

In summary, the DR3 Polyclonal Antibody is a highly reliable and versatile tool for the investigation of DR3 protein expression. Its exceptional performance, ease of use, and rigorous quality control make it an indispensable asset for researchers in the fields of immunology, cell biology, and molecular biology.