DJ-1 Polyclonal Antibody

The product of PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in PARK7 are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for PARK7.

The DJ-1 polyclonal antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of DJ-1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human DJ-1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards DJ-1 protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and ELISA.

The DJ-1 polyclonal antibody is supplied as a purified IgG fraction, which has been affinity-purified using a DJ-1 protein column. This ensures that the antibody is free from non-specific binding and contaminants, resulting in highly reproducible and reliable results. The antibody is provided in a liquid format, which can be easily diluted and used for various applications.

The DJ-1 polyclonal antibody has been extensively validated for its specificity and sensitivity towards DJ-1 protein. It has been shown to detect endogenous DJ-1 protein in various human tissues and cell lines, as well as recombinant DJ-1 protein expressed in bacterial and mammalian cells. The antibody has also been shown to be highly specific towards DJ-1 protein, with no cross-reactivity towards other proteins.

In summary, the DJ-1 polyclonal antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of DJ-1 protein in various biological samples. Its high affinity and specificity towards DJ-1 protein, as well as its extensive validation, make it a reliable tool for various applications in research and diagnostics.