DHRS2 Polyclonal Antibody

DHRS2 (dehydrogenase/reductase (SDR family) member 2), also known as SDR25C1 or HEP27, is a 258 amino acid protein that localizes to the nucleus and belongs to the short-chain dehydrogenase/reductase (SDR) family. Functioning as an NADPH-dependent dicarbonyl reductase, DHRS2 is thought to inhibit cell replication by either converting cortisone in cortisol, or by catalyzing the oxidation of androgen and estrogen. The gene encoding DHRS2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

The DHRS2 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality materials and advanced techniques to ensure optimal performance and reliability. It is a polyclonal antibody that recognizes DHRS2, a member of the short-chain dehydrogenase/reductase (SDR) family of enzymes. DHRS2 is involved in the metabolism of various compounds, including retinoids, steroids, and fatty acids.

The DHRS2 Polyclonal Antibody is suitable for use in various techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for use in human, mouse, and rat samples. This antibody is an essential tool for researchers studying the function and regulation of DHRS2 and its role in various physiological and pathological processes.