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BT Lab

SKU:BT-AP02544

DDX3Y Polyclonal Antibody

DDX3Y Polyclonal Antibody

Regular price $275.00 USD
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The protein encoded by DDX3Y (DEAD-box helicase 3, Y-linked) is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of DDX3Y is not complemented by DDX3X. Mutations in DDX3Y result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both DDX3Y and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

The DDX3Y Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of DDX3Y protein expression. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

The DDX3Y Polyclonal Antibody exhibits exceptional affinity and specificity towards DDX3Y, a member of the DEAD-box RNA helicase family. It is known to play a crucial role in various cellular processes, including RNA metabolism, translation initiation, and cell cycle progression. This antibody enables researchers to investigate the functional significance of DDX3Y in diverse biological contexts.

With its superior sensitivity, the DDX3Y Polyclonal Antibody allows for the detection of even low levels of DDX3Y protein expression. This feature is particularly advantageous when studying samples with limited protein availability or low expression levels. The antibody's high specificity ensures minimal cross-reactivity with other proteins, thereby providing accurate and reliable results.

The DDX3Y Polyclonal Antibody is compatible with various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for the examination of DDX3Y expression in different sample types, such as cell lysates, tissue sections, and cultured cells.

Furthermore, this antibody has been extensively validated in numerous research studies, demonstrating its consistent and reproducible performance. Its robustness and reliability make it an ideal choice for both basic research and clinical applications.

In summary, the DDX3Y Polyclonal Antibody is a highly specific and sensitive tool that enables researchers to investigate the role of DDX3Y in various biological processes. Its exceptional affinity, sensitivity, and specificity, along with its compatibility with multiple experimental techniques, make it an invaluable asset in the field of molecular biology and biomedical research.

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