DDX3 Polyclonal Antibody

DEAD-box helicase 3, X-linked encoded by DDX3X is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.

The DDX3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of DDX3 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards DDX3. With its exceptional sensitivity, this antibody enables accurate and precise quantification of DDX3 levels in both research and clinical settings.

The DDX3 Polyclonal Antibody exhibits excellent performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for the investigation of DDX3 expression patterns and localization in different tissues and cell types. Moreover, this antibody has been validated for use in multiple species, making it suitable for diverse experimental models.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. Its superior specificity minimizes the risk of cross-reactivity with other proteins, guaranteeing reliable and accurate results. Additionally, the DDX3 Polyclonal Antibody is provided in a convenient format, allowing for easy handling and storage.

In summary, the DDX3 Polyclonal Antibody is a valuable tool for researchers and clinicians seeking to investigate the role of DDX3 in various biological processes. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset in the field of molecular biology and biomedical research.