Cytokeratin 8 (Acetyl Lys483) Polyclonal Antibody

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.

The Cytokeratin 8 (Acetyl Lys483) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Cytokeratin 8 protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure its exceptional performance and reliability.

Cytokeratin 8 is a crucial intermediate filament protein that plays a significant role in maintaining the structural integrity of epithelial cells. It is widely expressed in various tissues, including liver, lung, kidney, and gastrointestinal tract. Abnormal expression or dysregulation of Cytokeratin 8 has been associated with numerous pathological conditions, making it an important target for research and diagnostic purposes.

The Cytokeratin 8 (Acetyl Lys483) Polyclonal Antibody exhibits high affinity and specificity towards Cytokeratin 8 protein, enabling accurate and precise detection. It has been validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody demonstrates excellent sensitivity, allowing for the detection of even low levels of Cytokeratin 8 protein in complex biological samples.

Furthermore, the Cytokeratin 8 (Acetyl Lys483) Polyclonal Antibody has been rigorously tested to ensure its reliability and reproducibility. It exhibits minimal cross-reactivity with other related proteins, ensuring specific detection of Cytokeratin 8. Additionally, it demonstrates excellent stability and consistency, providing consistent and reliable results across multiple experiments.

In summary, the Cytokeratin 8 (Acetyl Lys483) Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Cytokeratin 8 protein. Its exceptional sensitivity, specificity, and stability make it an ideal choice for researchers and clinicians involved in studying and diagnosing various pathological conditions associated with Cytokeratin 8 dysregulation.