Cytokeratin 18 Polyclonal Antibody

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for KRT18.

The Cytokeratin 18 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Cytokeratin 18 (CK18) protein expression. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional quality and performance.

Cytokeratin 18 is a member of the intermediate filament family of proteins and is predominantly expressed in epithelial cells. It plays a crucial role in maintaining the structural integrity of epithelial tissues and is involved in various cellular processes, including cell migration, adhesion, and signaling.

The Cytokeratin 18 Polyclonal Antibody exhibits excellent specificity towards CK18, enabling accurate identification and quantification of CK18 expression levels in various biological samples. It has been extensively validated for use in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

This antibody demonstrates exceptional sensitivity, allowing for the detection of low levels of CK18 expression. It exhibits minimal cross-reactivity with other cytokeratin isoforms, ensuring reliable and precise results. The high affinity of this antibody towards CK18 ensures optimal signal-to-noise ratio and minimal background interference.

The Cytokeratin 18 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation procedures. It is compatible with a wide range of sample types, including formalin-fixed paraffin-embedded (FFPE) tissues, frozen sections, and cell cultures.

With its superior performance characteristics, the Cytokeratin 18 Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in studying epithelial biology, cancer research, and diagnostic applications. Its reliable and accurate results make it an ideal choice for investigating CK18 expression patterns and its potential implications in various diseases and conditions.

Order the Cytokeratin 18 Polyclonal Antibody today and unlock new insights into the role of CK18 in cellular processes and disease progression.