Cytokeratin 14/16 Polyclonal Antibody

KRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

The Cytokeratin 14/16 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of cytokeratin 14 and 16 proteins in various biological samples. This antibody is produced by immunizing rabbits with synthetic peptides corresponding to the C-terminal regions of human cytokeratin 14 and 16 proteins. The resulting polyclonal antibody exhibits high affinity and specificity towards cytokeratin 14 and 16 proteins, making it an ideal tool for various research applications, including immunohistochemistry, western blotting, and ELISA. The Cytokeratin 14/16 Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

This antibody is suitable for use in both research and diagnostic applications and is available in various sizes to meet the needs of different experimental setups. With its high specificity and sensitivity, the Cytokeratin 14/16 Polyclonal Antibody is an essential tool for researchers studying the role of cytokeratin 14 and 16 proteins in various biological processes.