Cytokeratin 14 Polyclonal Antibody

KRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

The Cytokeratin 14 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Cytokeratin 14 protein expression in various biological samples. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards Cytokeratin 14.

Cytokeratin 14 is a crucial intermediate filament protein that plays a significant role in maintaining the structural integrity of epithelial cells. It is predominantly expressed in basal cells of stratified epithelia, such as the epidermis, oral mucosa, and hair follicles. Aberrant expression or mutations in Cytokeratin 14 have been associated with various pathological conditions, including skin disorders and certain types of cancer.

The Cytokeratin 14 Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal tool for immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications. It recognizes both native and denatured forms of Cytokeratin 14, enabling comprehensive analysis of protein expression in different experimental settings.

This antibody has been extensively validated using a wide range of human and animal tissue samples, ensuring reliable and reproducible results. It exhibits minimal cross-reactivity with other cytokeratins, ensuring accurate and specific detection of Cytokeratin 14.

The Cytokeratin 14 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling.

In summary, the Cytokeratin 14 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Cytokeratin 14 protein expression. Its exceptional sensitivity and specificity, along with its ease of use, make it an invaluable asset for researchers and clinicians studying epithelial biology, skin disorders, and cancer.