Cystatin E/M Polyclonal Antibody

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

The Cystatin E/M Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cystatin E/M protein in various biological samples. This antibody is produced using advanced techniques, ensuring its high affinity and specificity towards Cystatin E/M.

Cystatin E/M is a member of the cystatin superfamily, which plays a crucial role in regulating protease activity and maintaining protease-antiprotease balance. It is primarily expressed in epithelial tissues and has been implicated in various physiological and pathological processes, including cancer progression, inflammation, and tissue remodeling.

The Cystatin E/M Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). It recognizes both the native and denatured forms of Cystatin E/M, making it suitable for a wide range of experimental settings.

With its high sensitivity and specificity, this antibody enables accurate and reliable detection of Cystatin E/M protein levels, facilitating in-depth research and understanding of its biological functions. Its polyclonal nature ensures enhanced signal amplification, resulting in robust and reproducible results.

Furthermore, the Cystatin E/M Polyclonal Antibody has been rigorously validated for its performance and quality. It is manufactured under strict quality control measures, ensuring batch-to-batch consistency and reliability. Each vial is accompanied by a detailed datasheet, providing comprehensive information on its recommended usage, storage conditions, and handling instructions.

In summary, the Cystatin E/M Polyclonal Antibody is a valuable tool for researchers and scientists involved in studying Cystatin E/M protein and its associated biological processes. Its exceptional sensitivity, specificity, and reliability make it an indispensable asset in various research applications, contributing to advancements in the field of protease regulation and related diseases.