Cystatin 11 Polyclonal Antibody

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms.

The Cystatin 11 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of Cystatin 11 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cystatin 11 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards Cystatin 11 protein, making it an ideal tool for various research applications, including Western blotting, immunohistochemistry, and ELISA.

The Cystatin 11 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography. This ensures high purity and minimal cross-reactivity with other proteins, thereby enhancing the accuracy and reliability of experimental results. With its exceptional sensitivity and specificity, the Cystatin 11 Polyclonal Antibody is an indispensable tool for researchers studying the role of Cystatin 11 in various physiological and pathological processes.