CysLTR1 Polyclonal Antibody

CYSLTR1 encodes a member of the G-protein coupled receptor 1 family. The cysteinyl leukotriene receptor 1 is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

The CysLTR1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CysLTR1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CysLTR1 protein. The antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The CysLTR1 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting CysLTR1 protein in various biological samples, including human, mouse, and rat tissues. This antibody has been shown to recognize a single band of the expected molecular weight in Western blotting analysis and to exhibit strong staining in immunohistochemistry and immunofluorescence assays.

This antibody is an essential tool for researchers studying the role of CysLTR1 protein in various physiological and pathological processes, including inflammation, asthma, and cancer. Its high specificity and sensitivity make it an ideal reagent for the detection and quantification of CysLTR1 protein in various biological samples. The CysLTR1 Polyclonal Antibody is available in various sizes and formats to meet the specific needs of researchers.