CYP3A4 Polyclonal Antibody

CYP3A4 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

The CYP3A4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of CYP3A4 protein expression. This antibody has been extensively validated for its exceptional sensitivity and specificity, making it an ideal choice for various research applications.

The CYP3A4 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested against a wide range of samples, including human tissues and cell lines, to guarantee its reliability and accuracy.

This antibody exhibits excellent performance in various experimental techniques, such as Western blotting, immunohistochemistry, and immunofluorescence. It recognizes the CYP3A4 protein with high affinity, enabling precise and reproducible results.

With its exceptional specificity, the CYP3A4 Polyclonal Antibody offers researchers a valuable tool for studying the expression and function of CYP3A4 in various biological systems. It provides a reliable means to investigate the role of CYP3A4 in drug metabolism, drug-drug interactions, and personalized medicine.

The CYP3A4 Polyclonal Antibody is supplied in a convenient format, allowing for easy handling and storage. It is provided in a liquid form, ready-to-use for immediate application in your experiments. Each batch is accompanied by detailed documentation, including quality control data and recommended protocols, to ensure optimal performance.

Choose the CYP3A4 Polyclonal Antibody for its exceptional specificity, reliability, and versatility. It is an indispensable tool for researchers in the fields of pharmacology, toxicology, and drug development, facilitating groundbreaking discoveries and advancements in the understanding of CYP3A4 biology.