CYP2E1 Polyclonal Antibody

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cytochrome P450 2E1 localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

The CYP2E1 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of the cytochrome P450 2E1 (CYP2E1) protein. This antibody is produced using a polyclonal approach, which ensures a high degree of specificity and sensitivity for the target protein. The CYP2E1 Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is designed to recognize the CYP2E1 protein in a variety of species, including human, mouse, and rat. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results. The CYP2E1 Polyclonal Antibody is supplied in a convenient format, with a concentration of 1 mg/mL, allowing for easy and efficient use in a variety of experimental settings.

In summary, the CYP2E1 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of the CYP2E1 protein. Its versatility and reliability make it an ideal choice for researchers in a variety of fields, including pharmacology, toxicology, and biochemistry.