CYP2D6 Polyclonal Antibody

CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cytochrome P450 2D6 localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The CYP2D6 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of the CYP2D6 protein. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards the target protein. With its exceptional sensitivity, this antibody enables accurate and precise analysis of CYP2D6 expression levels in various biological samples.

The CYP2D6 Polyclonal Antibody exhibits excellent performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for the investigation of CYP2D6 expression patterns in different tissues and cell types, facilitating comprehensive research in the field of drug metabolism and personalized medicine.

This antibody is manufactured using state-of-the-art techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. Its superior performance characteristics, such as low background signal and high signal-to-noise ratio, guarantee reliable and accurate results in every experiment.

Furthermore, the CYP2D6 Polyclonal Antibody is provided in a convenient and user-friendly format, allowing for easy handling and storage. Its long shelf life ensures prolonged usability, making it an ideal choice for both academic and industrial laboratories.

In summary, the CYP2D6 Polyclonal Antibody is a highly specific, sensitive, and reliable tool for the detection and quantification of the CYP2D6 protein. Its exceptional performance characteristics, versatility, and user-friendly format make it an indispensable asset for researchers in the field of drug metabolism and personalized medicine.