CYP2A13 Polyclonal Antibody

CYP2A13 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4- (methylnitrosamino)-1- (3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. CYP2A13 is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

The CYP2A13 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CYP2A13 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards the target protein.

The CYP2A13 enzyme belongs to the cytochrome P450 superfamily and is primarily expressed in the human respiratory tract. It plays a crucial role in the metabolism of numerous xenobiotics, including tobacco-specific nitrosamines, which are potent carcinogens found in cigarette smoke. Therefore, the accurate measurement of CYP2A13 protein expression is of great importance in understanding the impact of tobacco smoke on human health.

This polyclonal antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other cytochrome P450 isoforms, ensuring reliable and specific results.

With its high sensitivity and specificity, the CYP2A13 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the role of CYP2A13 in carcinogenesis, drug metabolism, and toxicology. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.

Order your CYP2A13 Polyclonal Antibody today and unlock new insights into the intricate mechanisms of xenobiotic metabolism and its implications in human health and disease.