CYP24A1 Polyclonal Antibody

CYP24A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The CYP24A1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CYP24A1 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and specificity towards the target protein.

CYP24A1, also known as 25-hydroxyvitamin D-24-hydroxylase, plays a crucial role in the metabolism of vitamin D. It catalyzes the conversion of 25-hydroxyvitamin D3 to the biologically inactive form, 24,25-dihydroxyvitamin D3. Dysregulation of CYP24A1 has been implicated in various diseases, including vitamin D-related disorders, hypercalcemia, and certain cancers.

The CYP24A1 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been rigorously validated to ensure reliable and reproducible results, making it an ideal choice for both research and diagnostic purposes.

This antibody is produced using high-quality materials and undergoes stringent quality control measures to ensure batch-to-batch consistency and optimal performance. It is supplied as a liquid formulation, ready for immediate use, and is compatible with various assay conditions and protocols.

In summary, the CYP24A1 Polyclonal Antibody is a valuable tool for investigating the expression and function of CYP24A1 protein. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset for researchers and clinicians alike in the field of vitamin D metabolism and related disorders.