CYP1B1 Polyclonal Antibody

CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in CYP1B1 have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

The CYP1B1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CYP1B1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CYP1B1 protein. The resulting polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The CYP1B1 protein is a member of the cytochrome P450 family of enzymes, which play a crucial role in the metabolism of various endogenous and exogenous compounds. CYP1B1 is primarily expressed in the liver, but it is also found in other tissues, including the lung, kidney, and brain. Aberrant expression of CYP1B1 has been linked to various diseases, including cancer, cardiovascular disease, and glaucoma.

The CYP1B1 Polyclonal Antibody is an essential tool for researchers studying the role of CYP1B1 in various biological processes and diseases. Its high specificity and sensitivity make it an ideal reagent for detecting CYP1B1 protein expression in various samples, including tissue lysates, cell lysates, and biological fluids. This antibody is available in various sizes and formats to suit different experimental needs, and it is manufactured to the highest quality standards to ensure reproducible and reliable results.