CYP1A1/2 Polyclonal Antibody

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

The CYP1A1/2 Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of cytochrome P450 1A1 and 1A2 proteins. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The CYP1A1/2 Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and ELISA. It is designed to recognize both the human and mouse CYP1A1/2 proteins, making it a versatile tool for researchers working in various fields of study. With its exceptional performance and reliability, the CYP1A1/2 Polyclonal Antibody is an essential tool for any laboratory conducting research on cytochrome P450 1A1 and 1A2 proteins.