Cyclophilin D Polyclonal Antibody

Peptidyl-prolyl cis-trans isomerase D encoded by PPID is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A.

The Cyclophilin D Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cyclophilin D protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability.

Cyclophilin D is a crucial mitochondrial protein that plays a pivotal role in the regulation of cell death pathways, particularly in the context of mitochondrial permeability transition pore (mPTP) opening. By binding to Cyclophilin D, this antibody enables researchers to investigate the involvement of Cyclophilin D in various physiological and pathological processes, including neurodegenerative diseases, ischemia-reperfusion injury, and cancer.

The Cyclophilin D Polyclonal Antibody exhibits outstanding specificity, displaying minimal cross-reactivity with other related proteins. Its high sensitivity allows for the detection of low levels of Cyclophilin D, facilitating accurate and precise quantification. This antibody has been extensively validated in a range of experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring its suitability for diverse research applications.

With its exceptional quality and performance, the Cyclophilin D Polyclonal Antibody is an indispensable tool for scientists and researchers studying the intricate mechanisms underlying cell death pathways and their implications in various diseases. Its reliable and reproducible results make it an invaluable asset in advancing our understanding of Cyclophilin D biology and its potential as a therapeutic target.