Cyclin F Polyclonal Antibody

CCNF encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. Cyclin F encoded by CCNF belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

The Cyclin F Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cyclin F protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

Cyclin F is a crucial regulator of cell cycle progression and plays a pivotal role in maintaining genomic stability. It is involved in the degradation of several key cell cycle regulators, including p21 and p27, thereby promoting cell cycle progression. Dysregulation of Cyclin F has been implicated in various diseases, including cancer.

The Cyclin F Polyclonal Antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its ability to specifically recognize Cyclin F protein in various cell lines and tissues.

This antibody is produced using high-quality materials and undergoes rigorous quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage.

With its exceptional specificity and sensitivity, the Cyclin F Polyclonal Antibody is an indispensable tool for researchers and scientists studying cell cycle regulation, cancer biology, and related fields. Its reliable performance and ease of use make it an ideal choice for accurate and precise detection of Cyclin F protein in diverse experimental settings.