Cyclin B1 Polyclonal Antibody

The protein encoded by CCNB1 (cyclin B1) is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

The Cyclin B1 Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect Cyclin B1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cyclin B1 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The Cyclin B1 Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples and has been shown to exhibit minimal cross-reactivity with other Cyclin family members.

This antibody is an essential tool for researchers studying cell cycle regulation and the role of Cyclin B1 in various cellular processes, including mitosis and meiosis. Its high specificity and sensitivity make it an ideal choice for detecting Cyclin B1 protein expression levels in various biological samples.

In summary, the Cyclin B1 Polyclonal Antibody is a reliable and effective tool for detecting Cyclin B1 protein expression in various biological samples. Its high specificity and sensitivity make it an essential tool for researchers studying cell cycle regulation and the role of Cyclin B1 in various cellular processes.