CRSP130 Polyclonal Antibody

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. Mediator complex subunit 23 encoded by MED23 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for MED23.

The CRSP130 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CRSP130 protein expression in various biological samples. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the CRSP130 protein sequence.

The CRSP130 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise identification of CRSP130 protein in Western blotting, immunohistochemistry, and immunofluorescence applications. It has been extensively validated and optimized to ensure consistent and reproducible results across different experimental conditions.

With its superior performance, the CRSP130 Polyclonal Antibody offers researchers a valuable tool for investigating the role of CRSP130 protein in various cellular processes and disease mechanisms. Its versatility allows for a wide range of applications, including but not limited to, protein-protein interaction studies, functional analysis, and biomarker discovery.

Furthermore, the CRSP130 Polyclonal Antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reliability. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps.

In summary, the CRSP130 Polyclonal Antibody is a highly specific, sensitive, and reliable tool that enables accurate detection and analysis of CRSP130 protein expression. Its versatility and consistent performance make it an invaluable asset for researchers in various fields of biological and medical research.