CRF-RI Polyclonal Antibody

CRHR1 encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The corticotropin releasing hormone receptor 1 is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID: 147081 results in transcripts that encode isoforms that share similarity with the products of this gene.

The CRF-RI Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of Corticotropin-Releasing Factor Receptor I (CRF-RI) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the extracellular domain of human CRF-RI. The resulting polyclonal antibody exhibits high affinity and specificity towards CRF-RI, making it an ideal tool for various applications in research and diagnostics.

The CRF-RI Polyclonal Antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other related proteins. This antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different applications.

In summary, the CRF-RI Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of CRF-RI in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians working in the fields of neuroscience, endocrinology, and immunology.