CREB-2 Polyclonal Antibody

ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

The CREB-2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CREB-2 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its exceptional quality and performance.

The CREB-2 Polyclonal Antibody exhibits a high affinity towards the target protein, allowing for accurate and sensitive detection. It has been extensively validated in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody demonstrates excellent specificity, displaying minimal cross-reactivity with other proteins, thus ensuring reliable and precise results.

With its superior sensitivity, the CREB-2 Polyclonal Antibody enables the detection of even low levels of CREB-2 protein expression, making it an ideal choice for both qualitative and quantitative analysis. Its robust performance and consistent results make it an indispensable tool for researchers studying the role of CREB-2 in various biological processes.

The CREB-2 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, ensuring ease of handling and minimizing the risk of sample contamination. The antibody is also available in different sizes to accommodate various experimental needs.

In summary, the CREB-2 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of CREB-2 protein expression. Its exceptional sensitivity, excellent specificity, and convenient format make it an invaluable asset for researchers in the field of molecular biology and beyond.