Creatine Kinase M Polyclonal Antibody

Creatine kinase, M-typeencoded by CKM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

The Creatine Kinase M Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of Creatine Kinase M in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Creatine Kinase M. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal reagent for a wide range of applications, including Western blotting, ELISA, immunohistochemistry, and immunofluorescence.

The Creatine Kinase M Polyclonal Antibody is designed to recognize both the native and denatured forms of the protein, ensuring accurate and reliable results in various experimental conditions. This antibody has been extensively validated in multiple species, including human, mouse, rat, and other mammals, and has been shown to exhibit minimal cross-reactivity with other isoforms of Creatine Kinase.

The Creatine Kinase M Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using Protein A chromatography. The antibody is provided in a liquid format, ready to use for various applications. The product is shipped with detailed instructions for use, including recommended dilutions and storage conditions.

Overall, the Creatine Kinase M Polyclonal Antibody is a reliable and high-quality reagent for the detection and quantification of Creatine Kinase M in various biological samples. Its high specificity, sensitivity, and versatility make it an essential tool for researchers in the fields of biochemistry, cell biology, and molecular biology.