Cortactin Polyclonal Antibody

Cortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F-actin and Arp2/3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin exist due to the alternative splicing.

The Cortactin Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of cortactin protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

The Cortactin Polyclonal Antibody exhibits exceptional affinity and specificity towards cortactin, a key regulator of actin cytoskeleton dynamics and cell migration. It recognizes both the full-length cortactin protein and its various isoforms, making it suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its superior sensitivity, this antibody enables accurate and reliable quantification of cortactin expression levels in different cell types and tissues. Its robust performance ensures consistent and reproducible results, making it an ideal choice for both basic research and clinical investigations.

The Cortactin Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. Each batch is rigorously tested to meet stringent quality control standards, ensuring optimal performance and reliability.

In summary, the Cortactin Polyclonal Antibody is a valuable tool for researchers and scientists studying cortactin protein and its role in cellular processes. Its high specificity, sensitivity, and consistency make it an indispensable asset in various applications, facilitating groundbreaking discoveries and advancements in the field of molecular biology.