Connexin-40 Polyclonal Antibody

GJA5 is a member of the connexin gene family. The gap junction protein alpha 5 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

The Connexin-40 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Connexin-40 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards Connexin-40.

Connexin-40, also known as GJA5, is a member of the connexin family of proteins, which are integral membrane proteins involved in the formation of gap junctions. Gap junctions play a crucial role in intercellular communication, allowing the direct exchange of ions, metabolites, and signaling molecules between adjacent cells. Connexin-40 is predominantly expressed in the cardiovascular system, particularly in the atria and ventricles of the heart, where it contributes to the regulation of cardiac conduction and rhythm.

The Connexin-40 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other connexin family members, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The Connexin-40 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reproducibility.

In summary, the Connexin-40 Polyclonal Antibody is a valuable tool for researchers studying Connexin-40 protein expression and its role in intercellular communication, particularly in the cardiovascular system. Its high specificity, sensitivity, and reliability make it an essential component of any scientific investigation in this field.