COL4A1 Polyclonal Antibody

COL4A1 encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in COL4A1 cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.

The COL11A2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of COL11A2 protein expression. This antibody is produced through a rigorous process, ensuring its high quality and reliability. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The COL11A2 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the COL11A2 protein without cross-reactivity to other related proteins. Its sensitivity enables the detection of even low levels of COL11A2 expression, making it an ideal choice for both qualitative and quantitative analysis.

This antibody is manufactured using advanced techniques and state-of-the-art equipment, guaranteeing batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, allowing for easy handling and convenient storage. The antibody is provided in a range of sizes to accommodate various experimental needs.

With its exceptional performance characteristics, the COL11A2 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the role of COL11A2 in various biological processes and diseases. Its reliable and accurate results make it an invaluable asset in the field of molecular biology and biomedical research.

Please note that this product is for research use only and is not intended for diagnostic or therapeutic purposes.