COL11A2 Polyclonal Antibody

COL11A2 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

The COL11A2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of COL11A2 protein expression. This antibody is produced through a rigorous process, ensuring its high quality and reliability. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The COL11A2 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the COL11A2 protein without cross-reactivity to other related proteins. Its sensitivity enables the detection of even low levels of COL11A2 expression, making it an ideal choice for both qualitative and quantitative analysis.

This antibody is manufactured using advanced techniques and state-of-the-art equipment, guaranteeing batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, allowing for easy handling and convenient storage. The antibody is provided in a range of sizes to accommodate various experimental needs.

With its exceptional performance characteristics, the COL11A2 Polyclonal Antibody is an indispensable tool for researchers and scientists studying the role of COL11A2 in various biological processes and diseases. Its reliable and accurate results make it an invaluable asset in the field of molecular biology and biomedical research.

Please note that this product is for research use only and is not intended for diagnostic or therapeutic purposes.