CLIC3 Polyclonal Antibody

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3  (CLIC3)is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.

The Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cleaved caspase-6 p18 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional affinity and selectivity towards its target.

Caspase-6 is a crucial enzyme involved in the apoptotic pathway, playing a pivotal role in the execution phase of programmed cell death. Cleaved caspase-6 p18 is the active form of caspase-6, generated upon proteolytic cleavage. Its detection and quantification are of great significance in understanding the mechanisms underlying apoptosis and its dysregulation in various pathological conditions.

The Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other caspase family members, ensuring accurate and reliable results.

This antibody is supplied as a purified and concentrated solution, enabling optimal performance in a wide range of applications. It is compatible with multiple detection systems and can be used in both research and clinical settings. The Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody is provided in a convenient format, facilitating ease of use and storage.

In summary, the Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of cleaved caspase-6 p18 protein. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset for researchers and clinicians studying apoptosis and its implications in various diseases.