Cleaved-SUMO-2/3 (G93) Polyclonal Antibody

SUMO2 encodes small ubiquitin-like modifier 2 that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, small ubiquitin-like modifier 2 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for SUMO2. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

The Cleaved-SUMO-2/3 (G93) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cleaved SUMO-2/3 proteins. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its polyclonal nature, this antibody exhibits a broad reactivity towards cleaved SUMO-2/3 proteins, enabling comprehensive analysis of post-translational modifications. It recognizes the cleavage site at position G93, allowing for precise identification and characterization of SUMO-2/3 cleavage events.

The Cleaved-SUMO-2/3 (G93) Polyclonal Antibody demonstrates outstanding sensitivity, enabling the detection of even low abundance cleaved SUMO-2/3 proteins. Its high specificity ensures minimal cross-reactivity with non-target proteins, resulting in accurate and reliable data interpretation.

This antibody has been rigorously validated to ensure consistent performance and batch-to-batch reproducibility. It exhibits excellent stability, allowing for long-term storage without compromising its quality or functionality.

In summary, the Cleaved-SUMO-2/3 (G93) Polyclonal Antibody is a valuable tool for researchers studying SUMOylation and its role in cellular processes. Its exceptional sensitivity, specificity, and reliability make it an indispensable asset in the field of protein modification research.