Cleaved-MMP-10 (F99) Polyclonal Antibody

MMP10 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease (matrix metallopeptidase 10) breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. MMP10 is part of a cluster of MMP genes on chromosome 11.

The Cleaved-MMP-10 (F99) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of cleaved matrix metalloproteinase-10 (MMP-10) in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards the target protein.

Matrix metalloproteinases (MMPs) are a family of enzymes involved in the degradation and remodeling of the extracellular matrix. MMP-10, also known as stromelysin-2, plays a crucial role in tissue remodeling, wound healing, and various pathological processes. The cleaved form of MMP-10 is generated through proteolytic processing, which is associated with its activation and increased enzymatic activity.

The Cleaved-MMP-10 (F99) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings. It exhibits minimal cross-reactivity with other MMP family members, ensuring accurate and reliable results. This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA).

With its high specificity and sensitivity, the Cleaved-MMP-10 (F99) Polyclonal Antibody provides researchers with a valuable tool for studying the role of MMP-10 in various physiological and pathological processes. Its reliable performance and reproducibility make it an ideal choice for both basic research and clinical applications.

Order the Cleaved-MMP-10 (F99) Polyclonal Antibody today and unlock new insights into the function and regulation of MMP-10 in health and disease.