Cleaved-Integrin  Alpha5 LC (E895) Polyclonal Antibody

The product of ITGA5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of ITGA5 may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

The Cleaved-Integrin Alpha5 LC (E895) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of cleaved integrin alpha5 LC in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

Integrins are a family of transmembrane receptors that play a crucial role in cell adhesion and signaling. Cleavage of integrin alpha5 LC has been implicated in various physiological and pathological processes, including cell migration, invasion, and tumor metastasis. Therefore, the ability to accurately detect and quantify cleaved integrin alpha5 LC is of utmost importance in understanding these processes.

The Cleaved-Integrin Alpha5 LC (E895) Polyclonal Antibody exhibits exceptional sensitivity and selectivity, enabling precise detection of cleaved integrin alpha5 LC in complex biological samples. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is produced using high-quality materials and undergoes rigorous quality control procedures to ensure consistent performance and reproducibility. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of experimental conditions.

In summary, the Cleaved-Integrin Alpha5 LC (E895) Polyclonal Antibody is a valuable tool for researchers studying integrin biology and its involvement in cellular processes. Its high specificity, sensitivity, and versatility make it an ideal choice for accurate detection and analysis of cleaved integrin alpha5 LC in various experimental settings.