Cleaved-Cathepsin D LC (G65) Polyclonal Antibody

CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

The Cleaved-Cathepsin D LC (G65) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cleaved cathepsin D LC in various biological samples. This antibody is produced using advanced techniques and exhibits exceptional affinity and selectivity towards the target protein.

Cathepsin D is a lysosomal aspartic protease that plays a crucial role in various physiological and pathological processes, including protein degradation, cell death, and tumor progression. The cleaved form of cathepsin D LC has been identified as a key biomarker in several diseases, making it an important target for research and diagnostic purposes.

The Cleaved-Cathepsin D LC (G65) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The Cleaved-Cathepsin D LC (G65) Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue homogenates, and biological fluids.

With its exceptional performance characteristics and broad applicability, the Cleaved-Cathepsin D LC (G65) Polyclonal Antibody is an indispensable tool for researchers and clinicians involved in the study of cathepsin D and its role in various diseases. Its high specificity, sensitivity, and ease of use make it an ideal choice for accurate and reliable detection and quantification of cleaved cathepsin D LC in diverse biological samples.