Cleaved-Caspase-9 p35 (D315) Polyclonal Antibody

CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Introducing the Cleaved-Caspase-9 p35 (D315) Polyclonal Antibody, a highly reliable and efficient tool for the detection and analysis of cleaved Caspase-9 p35 protein. This antibody is meticulously designed and rigorously tested to ensure exceptional specificity and sensitivity, making it an indispensable asset for researchers in the field of apoptosis and cell death.

The Cleaved-Caspase-9 p35 (D315) Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing a high affinity and purity. It specifically recognizes the cleaved form of Caspase-9 p35, a crucial protein involved in the initiation of apoptosis. This antibody exhibits minimal cross-reactivity with other proteins, ensuring accurate and precise results.

With its exceptional sensitivity, this polyclonal antibody enables the detection of even low levels of cleaved Caspase-9 p35, facilitating the study of apoptotic pathways and their regulation. Its versatility allows for various applications, including Western blotting, immunohistochemistry, and immunofluorescence, providing researchers with a comprehensive toolkit for their investigations.

The Cleaved-Caspase-9 p35 (D315) Polyclonal Antibody is supplied in a convenient and user-friendly format, ensuring ease of use and storage. It is available in different sizes to accommodate diverse experimental needs. Each batch is subjected to rigorous quality control measures to guarantee consistent performance and reproducibility.

In summary, the Cleaved-Caspase-9 p35 (D315) Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of cleaved Caspase-9 p35 protein. Its exceptional sensitivity and versatility make it an invaluable asset for researchers in the field of apoptosis and cell death. Trust in this antibody to enhance your research and unlock new insights into the intricate mechanisms of programmed cell death.