Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

CASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.

Overexpression of the active form of caspase 5 induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by caspase 5; this process requires Fas-mediated dephosphorylation of Max.

The expression of CASP5 is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for CASP5.

The Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody is a highly specific and sensitive tool for the detection of cleaved caspase-5 p10 (S331) in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been rigorously tested for specificity and sensitivity.

The Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody is designed to recognize the cleaved form of caspase-5 p10 (S331) and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody is ideal for researchers studying apoptosis and cell death pathways, as well as those investigating the role of caspase-5 in various disease states. With its high specificity and sensitivity, the Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody is an essential tool for any researcher working in the field of cell biology.

The Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cleaved Caspase-5 p10 (S331) protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability.

Caspase-5 is a crucial enzyme involved in the regulation of programmed cell death, also known as apoptosis. The p10 fragment of Caspase-5 is generated upon activation and plays a significant role in the execution phase of apoptosis. The Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody specifically recognizes and binds to the cleaved form of Caspase-5 p10 at the serine 331 residue, enabling accurate detection and analysis of its expression levels.

This polyclonal antibody exhibits outstanding sensitivity and specificity, making it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated to ensure minimal cross-reactivity with other proteins, ensuring reliable and accurate results.

The Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is available in various sizes to accommodate different experimental requirements.

With its exceptional performance, reliability, and ease of use, the Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody is an indispensable tool for researchers and scientists studying apoptosis and its associated pathways. Trust in its superior quality to enhance your research and gain valuable insights into the intricate mechanisms of programmed cell death.