Cleaved-Bad (D71) Polyclonal Antibody

BCL2 associated agonist of cell death encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of BCL2 associated agonist of cell death. Alternative splicing of BAD results in two transcript variants which encode the same isoform.

The Cleaved-Bad (D71) Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection of cleaved Bad protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated to ensure optimal performance and reproducibility. The Cleaved-Bad (D71) Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated for its specificity and sensitivity, ensuring reliable and accurate results. This antibody is an essential tool for researchers studying apoptosis and cell death pathways, and it is available in various sizes to meet the needs of different experimental designs. With its exceptional performance and reliability, the Cleaved-Bad (D71) Polyclonal Antibody is an indispensable tool for researchers in the field of cell biology and molecular biology.