CLCC1 Polyclonal Antibody

Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLCC1 (Chloride channel CLIC-like protein 1), also known as MCLC (Mid-1-related chloride channel) or KIAA0761, is a 551 amino acid multi-pass membrane protein that belongs to the chloride channel MCLC family. CLCC1 is related to the Saccharomyces cerevisiae protein Mid-1 and is believed to function as an intracellular chloride channel that is expressed in lung, brain, muscle, liver and testis. Localizing to intracellular compartments such as the Golgi apparatus, the endoplasmic reticulum (ER) and the nuclear envelope, CLCC1 is expressed as four isoforms due to alternative splicing events, namely hMCLC-1, hMCLC-2, hMCLC-3 and hMCLC-4.

The CLCC1 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of CLCC1 protein expression in various biological samples. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the CLCC1 protein sequence.

The CLCC1 Polyclonal Antibody exhibits exceptional affinity and selectivity towards CLCC1, enabling accurate and reliable detection of this protein in Western blotting, immunohistochemistry, and immunofluorescence applications. It has been rigorously validated for its specificity, ensuring minimal cross-reactivity with other proteins.

With its superior sensitivity, the CLCC1 Polyclonal Antibody allows for the detection of even low levels of CLCC1 protein expression, making it an ideal choice for researchers studying the role of CLCC1 in various biological processes. Its robust performance and consistent results make it a valuable tool for both basic research and clinical applications.

The CLCC1 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is available in various sizes to accommodate different experimental needs. Each batch of antibody undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility.

In summary, the CLCC1 Polyclonal Antibody is a reliable and high-quality reagent that offers exceptional sensitivity and specificity for the detection and analysis of CLCC1 protein expression. Its versatility and performance make it an indispensable tool for researchers in the field of molecular biology, immunology, and biomedical sciences.