CLC-6 Polyclonal Antibody

CLCN6 encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. Chloride voltage-gated channel 6 is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown.

The Claudin-3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Claudin-3 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Claudin-3 is a key component of tight junctions, playing a crucial role in maintaining the integrity and barrier function of epithelial and endothelial cell layers. Dysregulation of Claudin-3 expression has been implicated in various pathological conditions, including cancer progression and metastasis.

The Claudin-3 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to Claudin-3 protein without cross-reactivity to other Claudin family members. It has been extensively validated in multiple experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody demonstrates superior sensitivity, enabling the detection of low levels of Claudin-3 protein expression. Its robust performance ensures reliable and accurate results, making it an ideal choice for both basic research and clinical applications.

The Claudin-3 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is available in various sizes to accommodate different experimental requirements.

With its exceptional specificity, sensitivity, and reliability, the Claudin-3 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of Claudin-3 in various physiological and pathological processes.