Claudin-5 Polyclonal Antibody

CLDN5 (claudin 5) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in CLDN5 have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for CLDN5.

The Claudin-5 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Claudin-5 protein expression in various biological samples. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards Claudin-5.

Claudin-5 is a crucial component of tight junctions, playing a vital role in maintaining the integrity and barrier function of endothelial cells. Dysregulation of Claudin-5 expression has been implicated in various pathological conditions, including cancer, inflammation, and neurological disorders.

The Claudin-5 Polyclonal Antibody exhibits exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications. It demonstrates minimal cross-reactivity with other Claudin family members, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use. It has been rigorously tested for quality and consistency, guaranteeing reproducible results across experiments.

With its exceptional sensitivity and specificity, the Claudin-5 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying tight junctions, endothelial cell biology, and related diseases.