Claudin-19 Polyclonal Antibody

The product of CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for CLDN19.

The CKR-7 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CKR-7 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity.

The CKR-7 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and proven to provide accurate and reproducible results.

With its superior specificity, the CKR-7 Polyclonal Antibody enables researchers to confidently investigate the role of CKR-7 in various physiological and pathological processes. Its exceptional sensitivity allows for the detection of low levels of CKR-7 expression, making it an invaluable tool for studying subtle changes in protein expression.

The CKR-7 Polyclonal Antibody is manufactured under strict quality control standards, ensuring batch-to-batch consistency and reliability. It is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming antibody preparation.

In summary, the CKR-7 Polyclonal Antibody is a highly reliable and specific tool that enables accurate detection and analysis of CKR-7 protein expression. Its exceptional performance and versatility make it an essential component for researchers studying CKR-7-related processes and diseases.