CKR-3 Polyclonal Antibody

C-C motif chemokine receptor 3 encoded by CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

The CKR-3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CKR-3 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. With its exceptional performance, the CKR-3 Polyclonal Antibody offers researchers a valuable resource for investigating the role of CKR-3 in cellular processes and disease mechanisms.

The CKR-3 Polyclonal Antibody exhibits excellent specificity, exhibiting minimal cross-reactivity with other related proteins. This feature guarantees accurate and precise results, enabling researchers to confidently interpret their experimental data. Furthermore, this antibody has been extensively validated in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring its versatility and reliability across different experimental setups.

The CKR-3 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its formulation has been optimized to provide optimal stability and long shelf life, ensuring consistent and reproducible results over time. Additionally, this antibody is available in various sizes to accommodate different experimental needs, allowing researchers to choose the most suitable option for their specific requirements.

In summary, the CKR-3 Polyclonal Antibody is a superior research tool that offers exceptional specificity, sensitivity, and versatility. Its reliable performance and ease of use make it an invaluable asset for scientists studying CKR-3 protein expression and its implications in various biological processes and diseases.